The Efficacy of Oxfendazole Against a Strain of Haemonchus contortus Resistant to Fenbendazole and Thiophanate
Keywords:
Worms, Anaemia, Antimicrobial Resistance, AntihelminticsAbstract
A critical controlled test was conducted to determine the efficacy of Oxfendazole against a strain of Haemonchus contortus isolated at Sokoine University of Agriculture (SUA) and known to be resistant to Fenbendazole and Thiophanate. A susceptible strain for comparison was obtained from Kimamba in Kilosa District. Based on post-mortem worm counts, the efficacy of Oxfendazole at the recommended dose of 5mg/kg body weight was 99.8% against Kimamba-strain but only 15% against SUA-strain. The results show that SUA-strain of H.contortus is highly resistant to Oxfendazole at the recommended dose
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