The use of alfaxalone on free ranging African Pygmy Hedgehog (Atelerix albiventris) premedicated with xylazine produces a stable and short term anaesthesia

Authors

  • D.G. Mpanduji Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine and Biomedical Sciences. Sokoine University of Agriculture, Morogoro Tanzania
  • S. Lokesh Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine and Biomedical Sciences. Sokoine University of Agriculture, Morogoro Tanzania
  • D.G. Ndossi Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine and Biomedical Sciences. Sokoine University of Agriculture, Morogoro Tanzania

Keywords:

Alfaxalone, xylazine, anaesthesia, African pygmy hedgehog, Atelerix albiventris

Abstract

The African wild pygmy hedgehog has been domesticated and widely used in scientific experiments. Anesthesia of hedgehogs appear to be challenging, commonly associated with peri-anesthetic mortality. Inhalant anaesthetics are the agents of choice while injectable agents are seldom used and there are no reports on the use of alfaxalone. Thus the aim of this study was to evaluate two anaesthesia protocols of alfaxalone combined with a fixed dose of xylazine in hedgehog. Two groups consisting of 10 hedgehogs each were used in the study. The first group received 8mg per kilogram while the second group received 12mg per kilogram of alfaxalone with xylazine premedication maintained at 1mg per kilogram. All drugs were administered intramuscularly. Induction time, duration of anaesthesia and pain reflexes were monitored and recorded. Cardinal Health parameters were recorded just before, and at the 10 and 20 minutes post injection of anaesthetics. The two doses of 8 and 12mg per kg of alfaxalone showed no differences on the induction time but induced profound anaesthesia that differed significantly and lasted for over 37 and 54 minutes respectively with spontaneous and uneventful recovery. The two doses maintained respiration rates within the ranges of pre injection values while significant depression was noted on heart rates and rectal temperatures. The two tested doses of alfaxalone were well tolerated and appear to be safe for induction of short duration anaesthesia in hedgehogs. However, further study to evaluate the cardiopulmonary dynamics and temperature regulation effects of the drug in question is recommended.

Published

07-10-2024

How to Cite

Mpanduji, D., Lokesh, S. and Ndossi, D. (2024) “The use of alfaxalone on free ranging African Pygmy Hedgehog (Atelerix albiventris) premedicated with xylazine produces a stable and short term anaesthesia”, Tanzania Veterinary Journal, 39(2), pp. 1–8. Available at: http://tvj.sua.ac.tz/vet2/index.php/TVJ/article/view/638 (Accessed: 10 February 2025).

Issue

Section

RESEARCH ARTICLES